MedsurgMaster

  Alprostadil [al-PROS-ta-dil] is a PGE, analog that is naturally produc ed in tissues such as seminal vesicles and cavernous tissues, in the placenta, and in the ductus arteriosus of the fetus. PGE, maintain s the patency of the ductus arteriosus during pregnancy. The d uctus closes after delivery and allows normal blood circulation between the lungs and the heart. In neonates with congenital heart conditions, administering alprostadil keeps the ductus open, allowing time until surgical correction is possible. Alprostadil is also used for erectile dysfunction .